Fit a limma model to continuous expression or score data

Use this adapter for microarray intensities, log-expression assays, pathway scores, or other approximately continuous outcomes. For counts, use de_voom() instead.

Usage

de_limma(x, experiment, formula, assay, contrasts = NULL, trend = FALSE, ...)

Arguments

x: A MultiAssayExperiment object.
experiment: Optional experiment name.
formula: Fixed-effect model formula.
assay: Assay name or one-based assay index.
contrasts: Optional contrast matrix passed to limma::contrasts.fit().
trend: Passed to limma::eBayes().
...: Additional arguments passed to limma::eBayes().

Value

A native MArrayLM object.